Topiramate (97240-79-4)

1. CAS RN:  97240-79-4
2. Structural Formula:         
3. Molecular formula & Molecular weight: C12H21NO8S        339.37
4. Appearance: It’s a white to off-white powder. Freely soluble in dichloromethane
5. Quality Standard:  USP32,  purity  ≥ 98.0%
 Identification Infrared Absorption
 The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation , as obtained in the Assay
Specific rotation Between -28.6° and -35.0°,measured at 20°
Water Not more than 0.5%
Residue on Ignition Not more than 0.1%
Heavy metals Not more than 10ppm
Related compounds by HPLC
(Test 1) Fructose not more than 0.3%
Compound A not more than 0.3%
Other individual impurity not more than 0.1%
Total impurities not more than 0.5%
Limit of sulfamate and sulfate Sulfamate ion not more than 0.10%;
Sulfate ion not more than 0.10%.
Assay                                                                  Topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis.
6. Usage: It’s a new drug of anticonvulsants.
7. Storage: It stored in sealed containers, cool and dry place, and away from light.
8. Packing:  Paper bucket, 25kg/package.
9. HS CODE: 2932 9990.90