牛蒡子苷元 (-)-Arctigenin
Antitumor agent
Lignan derivative, which shows antitumor, anti-inflammatory, immunomodulatory and neuroprotective activities. Down-regulates anti-apoptotic protein Bcl-XL2+. Blocks the activation of Akt (protein kinase B; PKB) induced by glucose starvation. . Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic and cytotoxic properties against Hep62 cells. Antagonist for platelet activating factor and Ca
PRODUCT PROPERTIES
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Alternative Name:
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(3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2-(3H)-furanone
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Source/Host:
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Isolated from Arctium lappa.
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Solubility:
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Soluble in DMSO (34mg/ml, heating, sonication); sparingly soluble in water.
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Long Term Storage:
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-20°C
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MW:
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372.4
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CAS:
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7770-78-7
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Formula:
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C21H24O6
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Purity:
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≥97% (HPLC)
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Appearance:
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White to off-white solid.
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普华仕科技发展有限公司 --Puhuashi Technology Development Co., Ltd
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